Collagen Refresh Review: Studies Checked

Is Collagen Refresh worth it?

Worth a look (5.5/10). Collagen Refresh discloses an exact amount for every ingredient on its label, including a substantial 4,000 mg of hydrolyzed bovine collagen and a genuinely high 426 mg of vitamin C, both reasonable for supporting the body's collagen production. The trouble is the page's central hook: it says a recent study in the 'Journal of the American College of Rheumatology' identified something called 'Extracellular Triple Helical Collagen' as the only collagen that helps joints. We could not find that study anywhere, that specific journal name does not match the real American College of Rheumatology journal, and it is not among the ten references listed at the bottom of the page. A similarly specific claim about a 2018 marine collagen trial in 70 women is also absent from the reference list. The underlying ingredients are reasonable; the headline science story built around them is not something we could verify.

What we liked

Every ingredient is disclosed with an exact, checkable dose
4,000 mg of hydrolyzed bovine collagen and 426 mg of vitamin C are solid, clinically plausible amounts
180-day 'empty jar' money-back guarantee, longer than most ClickBank supplements
Real company name, address and phone number on the label
Free shipping on the 6-jar bundle and a comparatively low $33 to $59 monthly cost

What we didn't

The headline 'Extracellular Triple Helical Collagen' study citation does not match any findable, real publication
Two specific ingredient studies (eggshell and marine collagen) are missing from the page's own reference list
"Doctor Formulated" is claimed with no doctor named anywhere
No single-jar option; entry price is $118 for two jars
Polypodium leucotomos and sodium hyaluronate are dosed below common study amounts

What is Collagen Refresh?

Collagen Refresh is a powder supplement from WellMe, mixed one to two scoops a day into water, sold in a berry lemonade flavor. Each 8.5 oz jar holds 30 servings (a one-month supply at one scoop a day). The sales page's core argument is that store-bought animal collagen cannot match a form it calls 'Refreshed Collagen,' supposedly the only collagen type your joints actually use, and that the formula's job is to help your body make more of that internal collagen while animal-derived collagen peptides give a faster, temporary boost.

The supplement facts label lists nine active ingredients with exact doses: vitamin C (426 mg), vitamin D2 (32 mcg), vitamin E (100 mg), vitamin B3/niacinamide (20 mg), copper as copper gluconate (2 mg), hydrolyzed bovine collagen (4,000 mg), eggshell membrane collagen (500 mg), marine collagen peptides (500 mg), calaguala powder (polypodium leucotomos, 150 mg), and sodium hyaluronate (40 mg). Notably, the vitamin D2 and B3 are on the label but are never mentioned or explained anywhere in the sales page's ingredient story.

WellMe is named with a real business address (1301 Ridgeview Drive, McHenry, IL, per the label, with a Bloomington, MN address also listed on the sales page) and phone number, and the label states the product is manufactured in an FDA-inspected, cGMP facility in the USA. It is sold through ClickBank, which appears on the buyer's bank statement and handles the guarantee.

Format: Powder supplement (berry lemonade flavor), 30 scoops per jar, 1 to 2 scoops a day mixed with water. Sold by: WellMe (sold through ClickBank).

What is on the Collagen Refresh label?

Each row compares what the label or sales page states with what published research used. When an amount is missing, there is nothing to compare, and we say so.

IngredientPer servingWhat research used

Vitamin CIn studied range426 mg (473% DV)Vitamin C is a required cofactor for collagen synthesis; deficiency halts collagen production entirelyA genuinely high, well-justified dose for supporting the body's own collagen-building enzymes.

Vitamin EIn studied range100 mg (667% DV)Vitamin E is studied for protecting collagen fibers from oxidative damageA high percentage of daily value, but within commonly used supplemental ranges; worth noting if you take other vitamin E sources.

Vitamin D2 and Vitamin B3 (Niacinamide)In studied range32 mcg (1,267 IU) D2; 20 mg B3Both are common general-nutrition vitaminsBoth appear on the supplement facts panel with exact doses but are never mentioned, explained or credited anywhere in the sales page's ingredient story, an odd omission for two of the label's nine actives.

Copper (as copper gluconate)In studied range2 mg (222% DV)Copper is required for lysyl oxidase and prolyl hydroxylase, enzymes involved in collagen cross-linking and synthesisA meaningfully high dose relative to typical dietary copper intake, consistent with the collagen-support role the page describes.

Hydrolyzed Bovine CollagenIn studied range4,000 mgA 2015 review of hydrolyzed collagen intake found benefits for joint and bone health and skin aging at doses in a similar multi-gram rangeThis is a substantial, clinically plausible dose of Type I collagen peptides.

Eggshell Membrane CollagenDifferent strain studied500 mgThe sales page cites 'a 2017 study published in the Journal of Dietary Supplements' for skin-tone and elasticity benefitsNo 2017 Journal of Dietary Supplements study appears anywhere in the page's own 'Scientific References' list, and we could not locate this specific study independently.

Marine Collagen PeptidesDifferent strain studied500 mgThe sales page cites 'a 2018 peer-reviewed study' of 70 women showing reduced crow's feet and increased skin hydrationThis specific trial is not in the page's reference list, and a targeted search could not locate it. The claim cannot be verified against a real, citable source.

Calaguala Powder (Polypodium Leucotomos, root)Below studied dose150 mgOral photoprotection studies with Polypodium leucotomos extract commonly use 240 mg to 480 mg a day150 mg is below the doses used in most published oral Polypodium leucotomos research.

Sodium HyaluronateBelow studied dose40 mgA 2019 review of hyaluronic acid research covers doses that are often higher than 40 mg a day for joint and skin outcomes40 mg is a modest amount relative to doses more commonly studied for joint comfort.

Every ingredient on the label carries an exact dose, which is a real transparency plus, and the hydrolyzed bovine collagen and vitamin C amounts are solid. But two of the page's specific supporting studies, for eggshell and marine collagen, do not appear in its own reference list and could not be independently verified, and the central 'Extracellular Triple Helical Collagen' claim traces to a journal citation that does not match any real, findable study.

Do the Collagen Refresh claims hold up?

"A recent study published in the esteemed Journal of the American College of Rheumatology revealed" that only a specific internal collagen ('Extracellular Triple Helical Collagen') supports joints

We could not find this study. The real journal published by the American College of Rheumatology is called Arthritis & Rheumatology, not the 'Journal of the American College of Rheumatology,' and no study matching this description appears in the page's own list of scientific references.

Marine collagen: a "2018 peer-reviewed study" of 70 women reduced crow's feet by 15% and increased skin hydration by 28%

This specific study is not included in the page's reference list, and a targeted search did not locate it. It cannot be verified.

Eggshell collagen: "A 2017 study published in the Journal of Dietary Supplements" showed reduced skin discoloration and 12% more elasticity

This study is likewise absent from the page's own reference list and could not be independently verified.

"Doctor Formulated" on the product label

No doctor is named anywhere on the sales page or label, so the claim cannot be checked against a real, credentialed formulator.

How much does Collagen Refresh really cost?

Option	Total	Per month	Shipping
2 jars	$118	$59	$9.95 US shipping
3 jars	$147	$49	$9.95 US shipping
6 jars	$198	$33	Free US shipping

There is no single-jar purchase option. The smallest bundle is 2 jars for $118 ($59 a jar) plus $9.95 US shipping, which the ClickBank order form totaled at $127.95. Three jars cost $147 ($49 a jar) plus $9.95 shipping, and six jars cost $198 ($33 a jar) with free US shipping.

At one scoop a day, one jar lasts 30 days, so the real monthly cost ranges from about $33 to $59 depending on the bundle, which is on the lower end for a collagen and joint-support powder in this category.

The 3 and 6 jar bundles add two digital bonus ebooks (on kitchen skin remedies and general healthy-aging habits), together valued on the page at $59.90. As digital downloads, they cost WellMe nothing to include and should not be treated as a reason to size up your order.

There is no single-jar purchase option; the smallest available bundle is two jars. The 2 and 3 jar bundles add $9.95 for US shipping, while the 6-jar bundle ships free. The sales page says US orders arrive in 5 to 7 business days.

Can you get a refund on Collagen Refresh?

180-day window. Both the sales page and the ClickBank order form state a 180-day 'empty jar' guarantee: a full refund even if every jar has been used, no questions asked. This is a longer window than the common 60-day ClickBank default.

Step by step: find the ClickBank receipt email, look up the order at clkbank.com and ask for a refund in writing. Our ClickBank refund guide covers returns, extra offers and auto-ship.

Which red flags did we find?

Headline study appears unfindableThe central 'Extracellular Triple Helical Collagen' claim cites a journal name that does not match the real American College of Rheumatology publication, and no matching study is in the page's reference list.
Two ingredient-specific studies missing from the reference listThe 2017 eggshell collagen study and the 2018 marine collagen study named in the sales copy do not appear among the page's own cited references.
Two labeled vitamins go unexplainedVitamin D2 and vitamin B3 appear on the supplement facts panel with exact doses but are never mentioned in the sales page's ingredient descriptions.
"Doctor Formulated" with no doctor namedThe label states the product is doctor formulated, but no name or credential appears anywhere on the sales page.
Polypodium and hyaluronic acid doses below common study amounts150 mg of Polypodium leucotomos and 40 mg of sodium hyaluronate are each lower than the amounts used in the research typically cited for those ingredients.

Who should buy Collagen Refresh, and who should skip it?

It may suit you if

You want a fully dosed collagen powder with a genuinely long, 180-day refund window, and you are comfortable that some of the page's specific supporting studies could not be verified.
You are comfortable buying at least two jars up front, since no single-jar option exists.

Skip it if

You specifically want the ingredients and doses tested in the exact studies a sales page cites; two of the named studies here could not be located.
You have a fish or egg allergy; the label discloses the product contains fish (pollock) and eggs from its marine and eggshell collagen sources.
You want a formula from a named, checkable doctor; the 'Doctor Formulated' claim here has no name attached.

How we assessed this

We did not buy or use Collagen Refresh. This review audits the offer as it appeared on September 28, 2026. We read:

The Collagen Refresh sales page (yourcollagensource.com/cb) reached through our ClickBank link
The product label image linked from the sales page, including the full supplement facts panel
The page's 'Scientific References' list of 10 citations
The ClickBank order form for a 2-jar order, confirming the $127.95 total and 180-day guarantee
Figueres Juher and Basés Pérez 2015, review of hydrolysed collagen intake for joint, bone and skin health (PubMed)
González et al. 1997, oral and topical Polypodium leucotomos photoprotection study (PubMed)

Sources

Scores: evidence 3.5, price 6, refund 8.5, transparency 4. How we score.

Collagen Refresh FAQ

Is Collagen Refresh legit?

It is a real product from a named company (WellMe) sold through ClickBank with a 180-day refund, not a scam that takes your money for nothing. The concern is scientific accuracy: its headline study citation does not match any real, findable publication, and two other cited studies are missing from its own reference list.

How much does Collagen Refresh cost?

There is no single-jar option. Two jars cost $118 ($59 each) plus $9.95 shipping, three jars cost $147 ($49 each) plus $9.95 shipping, and six jars cost $198 ($33 each) with free shipping. One jar lasts 30 days at one scoop a day.

What are the side effects of Collagen Refresh?

The label discloses the product contains fish (pollock) and eggs, from its marine and eggshell collagen sources, so it is not suitable for those allergies. It is otherwise free of gluten, dairy, nuts and soy per the label.

Does Collagen Refresh cure joint pain?

No. The label states the product is not intended to diagnose, treat, cure or prevent any disease, and joint discomfort with an unclear cause should be evaluated by a doctor.

How do I get a Collagen Refresh refund?

Both the sales page and the ClickBank order form state a 180-day, empty-jar, no-questions-asked guarantee. Use your ClickBank receipt email to find the order at clkbank.com and submit the refund request there.

Collagen Refresh review